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  • Title: Hot-injection synthesis of iron/iron oxide core/shell nanoparticles for T2 contrast enhancement in magnetic resonance imaging.
    Author: Herman DA, Ferguson P, Cheong S, Hermans IF, Ruck BJ, Allan KM, Prabakar S, Spencer JL, Lendrum CD, Tilley RD.
    Journal: Chem Commun (Camb); 2011 Aug 28; 47(32):9221-3. PubMed ID: 21761066.
    Abstract:
    Here we report a new, bench-top synthesis for iron/iron oxide core/shell nanoparticles via the thermal decomposition of Fe(η(5)-C(6)H(3)Me(4))(2). The iron/iron oxide core/shell nanoparticles are superparamagnetic at room temperature and show improved negative contrast in T(2)-weighted MR imaging compared to pure iron oxides nanoparticles, and have a transverse relaxivity (r(2)) of 332 mM(-1) s(-1).
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