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  • Title: Impact of human immunodeficiency virus coinfection on the progression of mother-to-child transmitted hepatitis C virus infection.
    Author: Claret-Teruel G, Noguera-Julian A, Esteva C, Muñoz-Almagro C, Sánchez E, Jiménez R, Fortuny C.
    Journal: Pediatr Infect Dis J; 2011 Sep; 30(9):801-4. PubMed ID: 21772231.
    Abstract:
    Data on mother-to-child transmitted human immunodeficiency virus/hepatitis C virus (HIV/HCV) coinfection are scarce. A prospective observational study with a cohort of 70 HCV-infected children (13 of whom were HIV/HCV-coinfected; mean follow-up: 7.3 years) is presented. In our series, surrogate markers of disease progression (HCV viremia, maximum alanine aminotransferase values, and spontaneous HCV infection clearance) suggest that the evolution of liver disease in HIV/HCV-coinfected pediatric patients is more aggressive than it is in HCV-only infected children.
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