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  • Title: Cutaneous metastasis of osteosarcoma in the scalp.
    Author: Ragsdale MI, Lehmer LM, Ragsdale BD, Chow WA, Carson RT.
    Journal: Am J Dermatopathol; 2011 Aug; 33(6):e70-3. PubMed ID: 21778830.
    Abstract:
    As a primary malignant bone tumor, osteosarcoma is second only to chondrosarcoma. Although it commonly metastasizes and is aggressive in nature, it rarely colonizes the skin. This is a report of a 22-year-old male with osteosarcoma of the pelvis and metastasis to the lungs and chest wall who developed a clinically unsuspected solitary cutaneous metastasis in the scalp. Instead of the expected cyst, incisional biopsy disclosed a solid tan nodule of chondro-osseous sarcoma. Although rare, cutaneous metastases from osteosarcoma may appear in skin, especially the scalp, or in skin over the primary tumor. New skin lesions in a patient with a history of osteosarcoma warrant investigations including imaging and biopsy.
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