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  • Title: Undifferentiated high-grade pleomorphic sarcoma in a blind eye with a silicone prosthesis implant: a clinico-pathologic study.
    Author: Piscitelli D, Ruggeri E, Fiore MG, Rossi R, Guerriero S.
    Journal: Orbit; 2011 Aug; 30(4):192-4. PubMed ID: 21780933.
    Abstract:
    PURPOSE: To describe a rare case of an orbital undifferentiated sarcoma arising in an eviscerated eye socket with a silicone implant. METHODS: The clinical and histopathological findings of the case are reviewed and presented. RESULTS: A patient who had undergone post-traumatic evisceration of the right eye and a silicone prosthesis implant 8 years earlier, presented to our observation with a painful eye, on which a brownish, bleeding mass, measuring 1 cm in diameter, was evident. After removal of the silicone prosthesis, the mass was found to arise from the scleral socket. Histopathological analysis demonstrated a malignant tumor composed of markedly pleomorphic cells with a high mitotic rate. An undifferentiated high-grade pleomorphic sarcoma was diagnosed. Complete right orbital exenteration was performed and the patient underwent radiotherapy CONCLUSIONS: This is the first report of an undifferentiated high-grade pleomorphic sarcoma arising from a scleral socket with a silicone implant.
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