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  • Title: Eumycetoma caused by Diaporthe phaseolorum (Phomopsis phaseoli): a case report and a mini-review of Diaporthe/Phomopsis spp invasive infections in humans.
    Author: Iriart X, Binois R, Fior A, Blanchet D, Berry A, Cassaing S, Amazan E, Papot E, Carme B, Aznar C, Couppié P.
    Journal: Clin Microbiol Infect; 2011 Oct; 17(10):1492-4. PubMed ID: 21781209.
    Abstract:
    Diaporthe phaseolorum (syn. Phomopsis phaseoli) is a frequent fungal parasite of plants, present on all continents around the world. It has rarely been involved in human diseases. We report a case of eumycetoma with osteomyelitis of the forefoot caused by this fungus and diagnosed by molecular biology. The patient had positive HTLV-1 serology and was a farmer from French Guiana who walked barefoot. He was successfully treated with long-term oral itraconazole (400 mg/day). A review of the literature underlines the essential roles of plants and host immunosuppression in this infection and the favourable outcome with a triazole antifungal treatment.
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