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  • Title: Multicenter, double-blind, placebo-controlled trial of triamcinolone acetonide nasal aerosol in the treatment of perennial allergic rhinitis.
    Author: Spector S, Bronsky E, Chervinsky P, Lotner G, Koepke J, Selner J, Pearlman D, Tinkelman D, Weakley S, Alderfer V.
    Journal: Ann Allergy; 1990 Mar; 64(3):300-5. PubMed ID: 2178497.
    Abstract:
    In a double-blind study involving 205 patients with perennial allergic rhinitis, statistically significantly greater symptomatic improvements were evident following the administration of 200 micrograms/day triamcinolone acetonide aerosol than following placebo. These improvements were evident as early as week 1 and were sustained throughout the 12-week study. They were accompanied by greater reductions in nasal eosinophils. Triamcinolone acetonide aerosol was well tolerated and had no effect on serum cortisol levels.
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