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Title: HIV-1-related thrombocytopenia. Author: Karpatkin S. Journal: Hematol Oncol Clin North Am; 1990 Feb; 4(1):193-218. PubMed ID: 2179211. Abstract: Immunologic thrombocytopenia has recently been described in HIV-1 seropositive patients: homosexuals, narcotic addicts, hemophiliacs, and heterosexual partners of HIV-1 infected patients. All patients have markedly elevated platelet-bound IgG and C3C4 as well as circulating immune complexes. The immune complexes of homosexuals and narcotic addicts contain anti-F(ab') against anti-HIV-1 antibody. These are present in the serum and on the platelets, and could be responsible for the thrombocytopenia.[Abstract] [Full Text] [Related] [New Search]