These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Silver-catalyzed regioselective carbomagnesiation of alkynes with alkyl halides and Grignard reagents.
    Author: Kambe N, Moriwaki Y, Fujii Y, Iwasaki T, Terao J.
    Journal: Org Lett; 2011 Sep 02; 13(17):4656-9. PubMed ID: 21806040.
    Abstract:
    A silver-catalyzed carbomagnesiation of alkynes with alkyl halides and Grignard reagents afforded alkenyl Grignard reagents regioselectively, where the alkyl group of the alkyl halide, but not that of the Grignard reagent, was introduced into the alkyne. Application to δ-haloalkylacetylenes yielded cyclopentanes or a tetrahydrofuran containing an exo-methylene substituent via 5-exo-dig cyclization.
    [Abstract] [Full Text] [Related] [New Search]