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  • Title: [The effect of whole-body and local irradiation, modified by hyperglycemia, on the metastasis of Walker carcinosarcoma 256 in rats].
    Author: Kutlimuratov AB, Ivashkin AV, Zakirkhodzhaev UD.
    Journal: Eksp Onkol; 1990; 12(2):76-9. PubMed ID: 2180678.
    Abstract:
    It has been shown that the local radiation therapy, and also radiation therapy modified by the short-term hyperglycemia really increase the life-span of rats with Walker 256 carcinosarcoma. At the same time the metastatic process also increases, especially after the modified radiation therapy. The total irradiation of experimental animals in a dose of 50 sGy before the modified radiation therapy considerably decreases the frequency of metastatic process. A conclusion is drawn that the total irradiation has a prophylactic influence on metastases under conditions of modified radiation therapy.
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