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  • Title: Long-QT syndrome.
    Author: Kramer DB, Zimetbaum PJ.
    Journal: Cardiol Rev; 2011; 19(5):217-25. PubMed ID: 21808164.
    Abstract:
    Acquired and hereditary long-QT syndromes are important causes of sudden cardiac death. Both categories are characterized by abnormally prolonged cardiac repolarization arising from a complex interaction between genetic and environmental factors. This produces a potentially dangerous substrate for polymorphic ventricular tachycardia and sudden cardiac death. In this review, the pathophysiologic, diagnostic, and prognostic features of long-QT syndromes, as well as recommendations regarding therapy, are reviewed.
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