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  • Title: [Granular-cell tumor (Abrikossoff's tumor): precise preoperative diagnosis is crucial when for minimally-invasive resection].
    Author: Karch HW, Gockel I, Goetz M, Kreft A, Lang H.
    Journal: Dtsch Med Wochenschr; 2011 Aug; 136(31-32):1609-12. PubMed ID: 21809253.
    Abstract:
    HISTORY AND ADMISSION FINDINGS: A 38-year-old man was referred to a gastroenterologist because of thoracic pain and dysphagia of uncertain cause. INVESTIGATIONS: Endoscopy revealed a centrally depressed, coarse submucosal tumor, 1.0 cm in diameter, in the anterior wall of the esophagus at about 35 cm from the teeth. Button-hole biopsy revealed histologically and immunohistochemically a granular cell tumor (Abrikossoff's tumor), positive for S-100 protein. CT-staging was unremarkable, except for a thickening of the distal esophageal wall. TREATMENT AND COURSE: Minimally invasive submucosal resection was undertaken using the videoscopic/endoscopic rendezvous technique. Histological examination confirmed complete resection of the tumor. The clinical course was uneventful and endoscopy 6 and 12 weeks after the operation showed complete resection of the tumor. CONCLUSION: An exact preoperative diagnosis beyond a mere description of site and morphology, but also providing the histopathological data creates favorable conditions for planning and performing a minimally invasive resection. Submucosal resection with the videoscopic/endoscopic in rendezvous technique offers the possibility of complete resection, which can often not be achieved in a submucosal tumor by only endoscopic resection.
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