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  • Title: Concurrent gastric MALT and Hodgkin lymphoma: a case report.
    Author: Oka K, Nagayama R, Yonekawa N, Nihei T, Sando N, Yatabe Y, Mori N.
    Journal: Int J Surg Pathol; 2012 Apr; 20(2):201-4. PubMed ID: 21813545.
    Abstract:
    This report describes a 60-year-old man with concurrent gastric extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) and classical Hodgkin lymphoma (CHL). Atypical, medium-sized, lymphoid cells proliferated in the mucosa to muscular layer of the stomach showing a lymphoepithelial lesion; admixed with Hodgkin/Reed-Sternberg (HRS) cells and an inflammatory cell background. MALT lymphoma cells expressed CD20, CD79a, PAX5, and BOB.1, and HRS cells expressed CD30, CD15, Epstein-Barr virus-encoded RNA, and EBV-latent membrane protein 1. Only CHL invaded into the regional lymph nodes. Two possibilities of transformation of MALT lymphoma into CHL and de novo CHL within MALT lymphoma are discussed.
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