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  • Title: [Opioid rotation: from theory to practice. Interdisciplinary recommendations from the Geneva University Hospitals pain network].
    Author: Roulet L, Luthy C, Garin N, Di Pollina de Gold L, Zoccatelli D, Escher Imhof M, Desmeules J, Piguet V.
    Journal: Rev Med Suisse; 2011 Jun 29; 7(301):1400-4, 1406. PubMed ID: 21815496.
    Abstract:
    Opioids are widely used to treat moderate to severe pain of cancer or non cancer origin. Although opioids provide an adequate analgesia in many patients, their use can be limited by inefficacy and/or intolerable side effects. Opioid rotation is one of the strategies that have been proposed to overcome these therapeutic difficulties. This article revisits the concept of opioid rotation, from pharmacological rational to clinical application.
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