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  • Title: Evaluation in rural practice of a rapid group B streptococcus screening test.
    Author: Yawn BP, Yawn RA, Henning T.
    Journal: Fam Med; 1990; 22(2):122-4. PubMed ID: 2182359.
    Abstract:
    Group B streptococcus (GBS) is the leading cause of infant mortality from infection. A rapid screening immunoassay for GBS was evaluated in a rural obstetrical population and was found to have an unacceptably low specificity (90%) and sensitivity (50%). With a culture proven GBS colonization rate of 6.8%, the positive predictive value of the rapid screening test was only 27%, and the negative predictive value was 96%. Current recommendations for routine vaginal cultures, on all women based on urban research data with high maternal colonization rates (15%-23%) and high prematurity rates (15%-40%) are reviewed in relation to this community's low colonization and prematurity rates.
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