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  • Title: Motor examination in children with Attention-deficit/hyperactivity Disorder and Asperger Syndrome.
    Author: Pasini A, D'Agati E, Pitzianti M, Casarelli L, Curatolo P.
    Journal: Acta Paediatr; 2012 Jan; 101(1):e15-8. PubMed ID: 21824190.
    Abstract:
    AIM: Evaluating whether motor skills could differentiate drug-naive subjects with two neurodevelopmental disorders: Attention-Deficit Hyperactivity Disorder (ADHD) and Asperger Syndrome (AS). METHODS: Thirty-six boys (12 with ADHD, 12 with AS and 12 with typical development) aged 8-12 were evaluated using the Physical and Neurological Examination for Subtle Signs. Three primary outcome variables were obtained as follows: (i) total speed of timed activities, (ii) total overflow and (iii) total dysrhythmia. RESULTS: Children with AS performed more slowly than those with ADHD and healthy children independently of age and IQ. Total dysrhythmia differentiates ADHD and AS children from controls. CONCLUSION: Dysfunction of the fronto-striatal-cerebellar networks related to motor control could be the physiopathological basis of the reported findings.
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