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  • Title: Piezoelectric-transducer-based miniature catheter for ultrahigh-speed endoscopic optical coherence tomography.
    Author: Tsai TH, Potsaid B, Kraus MF, Zhou C, Tao YK, Hornegger J, Fujimoto JG.
    Journal: Biomed Opt Express; 2011 Aug 01; 2(8):2438-48. PubMed ID: 21833379.
    Abstract:
    We developed a piezoelectric-transducer- (PZT) based miniature catheter with an outer diameter of 3.5 mm for ultrahigh-speed endoscopic optical coherence tomography (OCT). A miniaturized PZT bender actuates a fiber and the beam is scanned through a GRIN lens and micro-prism to provide high-speed, side-viewing capability. The probe optics can be pulled back over a long distance to acquire three-dimensional (3D) data sets covering a large area. Imaging is performed with 11 μm axial resolution in air (8 μm in tissue) and 20 μm transverse resolution, at 960 frames per second with a Fourier domain mode-locked laser operating at 480 kHz axial scan rate. Using a high-speed data acquisition system, endoscopic OCT imaging of the rabbit esophagus and colon in vivo and human colon specimens ex vivo is demonstrated.
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