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  • Title: Campylobacter pylori: a new pathogen.
    Author: Czinn SJ, Speck WT.
    Journal: Adv Pediatr Infect Dis; 1990; 5():221-37. PubMed ID: 2183821.
    Abstract:
    There is now considerable evidence suggesting that C. pylori is a human pathogen. The strong association between C. pylori and gastroduodenal disease is well documented. A number of hypotheses have been suggested for the pathogenic mechanisms of C. pylori-induced gastroduodenal disease, including the production of cytotoxins and the mechanical disruption of the epithelium. At the present time, treatment with a combination of antimicrobial agents eradicates the infection in approximately 50% of cases. Until an ideal therapeutic regimen is available, antimicrobial therapy is recommended only for those patients who continue to be symptomatic following 6 to 8 weeks of treatment with an H2-receptor.
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