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Title: Liver transplantation as treatment in a massive metastasis from Gruber-Frantz pancreatic tumor: a case report. Author: Dovigo AG, Díaz MB, Gütierrez MG, Selles CF, Grobas JP, Valladares M, Suárez F, Marini M. Journal: Transplant Proc; 2011; 43(6):2272-3. PubMed ID: 21839254. Abstract: The Gruber-Frantz tumor or solid pseudopapillary tumor of the pancreas accounts for 1% to 2% of pancreatic tumors. It occurs more frequently among women between 20 and 40 years of age and in the Asian population. These tumors are of low malignant potential and show slow growth. The symptoms are subtle, the most striking being pain and an abdominal mass. The most common site is the pancreatic tail. The location and local invasion determine the surgical technique. With R0 resection, survival is 95% at 5 years. In 15% of cases metastatic disease appears, mostly in the liver. The treatment of liver metastases is surgical resection. In the case of multiple liver metastases, the treatment is controversial. QT has been used, as well as radiofrequency ablation, arterial embolization, and intraarterial chemotherapy. Herein we have described the case of a 44-year-old woman with massive liver metastases who did not respond to QT lines and underwent successful liver transplantation with survival free of recurrence at 1 year later. This is the first liver transplantation for a metastatic pancreatic pseudopapillary tumor in Spain and the second described in the literature.[Abstract] [Full Text] [Related] [New Search]