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  • Title: Acanthosis nigricans as a local cutaneous side effect of repeated human insulin injections.
    Author: Buzási K, Sápi Z, Jermendy G.
    Journal: Diabetes Res Clin Pract; 2011 Nov; 94(2):e34-6. PubMed ID: 21839533.
    Abstract:
    Acanthosis nigricans is a hyperkeratotic lesion of the epidermis associated with insulin resistance. We present a diabetic patient with acanthosis nigricans at the insulin injection site on the abdominal wall. Neglecting rotation of sites for insulin injections and local hyperinsulinemia may play a role in the development of acanthosis nigricans.
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