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  • Title: Current issues in central venous catheter infection.
    Author: Toltzis P, Goldmann DA.
    Journal: Annu Rev Med; 1990; 41():169-76. PubMed ID: 2184721.
    Abstract:
    The majority of central venous line-associated infections are caused by organisms on the skin near the exit site gaining access to the intravascular segment of the catheter. A variety of strategies have been used in an effort to reduce catheter contamination, but one innovation--the semipermeable transparent dressing--may actually increase infection risk. On the other hand, new catheter materials and designs probably reduce the risk. There are only a limited number of well-designed studies of the increasingly popular totally implantable catheter system and the multilumen line, but it appears that the former is associated with a low rate of infection, while the latter may be more hazardous than the single-lumen line.
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