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  • Title: The first simultaneous study of the prevalence of Neisseria gonorrhoeae and Chlamydia trachomatis infections by polymerase chain reaction and standard methods.
    Author: Ouzounova-Raykova VV, El Tibi M, Mitov IG.
    Journal: Sex Health; 2011 Sep; 8(3):442-4. PubMed ID: 21851790.
    Abstract:
    BACKGROUND: Neisseria gonorrhoeae and Chlamydia trachomatis are important sexually transmissible pathogens. The aim of the present study was to determine their prevalence in symptomatic and asymptomatic people. METHODS: Polymerase chain reaction (PCR) and standard methods were tested for 413 specimens. RESULTS: The registered prevalence with PCR was N. gonorrhoeae 2.66% and C. trachomatis 0.73%. One man showed co-infection. Standard methods demonstrated lower sensitivity in finding N. gonorrhoeae and C. trachomatis in comparison with the PCR. CONCLUSIONS: This is the first simultaneous study in Bulgaria for detection of N. gonorrhoeae and C. trachomatis by PCR and standard methods. N. gonorrhoeae was found to be a more frequent infection. Further investigations are needed.
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