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  • Title: Clinical experience with ciprofloxacin: analysis of a multicenter study.
    Author: Karimi K.
    Journal: Indiana Med; 1990 Apr; 83(4):266-9. PubMed ID: 2185309.
    Abstract:
    In a multicenter study of 132 patients treated with ciprofloxacin for a variety of infections, 35 were microbiologically proven. Of these, bacteriologic cure equaled 85.7%, while improvement equaled 11.4%; failure was 2.9%. Clinical cure equaled 65.8%, while improvement was 26.3%. Failure was reported for 7.9% of cases. A total of 46 (35.9%) infections were classified as chronic. Overall, six of the 132 patients had adverse reactions. Two were related definitely to ciprofloxacin therapy. Therapy with ciprofloxacin was discontinued in two (1.5%) patients because of adverse effects.
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