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  • Title: Surgical outcome of community-acquired Clostridium difficile colitis presenting as toxic megacolon: case report.
    Author: Mann AP, McCague A, Lalezarzadeh F.
    Journal: Surg Infect (Larchmt); 2011 Aug; 12(4):317-20. PubMed ID: 21859335.
    Abstract:
    BACKGROUND: Over the past decade, there has been an increase in both community-acquired and health-care-associated Clostridium difficile colitis secondary to broad-spectrum antibiotic exposure. Toxic megacolon is a rare complication of pseudomembranous colitis that often necessitates emergency colectomy. METHODS: Review of the pertinent English-language literature. RESULTS: We present a case of community-acquired C. difficile colitis that made its initial presentation as fulminant toxic megacolon. Six months after a total colectomy, the patient has no complaints. CONCLUSION: Prompt total colectomy may improve survival in patients with toxic megacolon. The incidence of C. difficile-related toxic megacolon and post-operative outcomes of total colectomy should be investigated in a larger observational study.
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