These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Relapse of primary central nervous system lymphoma 13 years after high-dose methotrexate-based polychemotherapy.
    Author: Steinbeck JA, Stuplich M, Blasius E, Pels H, Glas M, Schlegel U, Herrlinger U.
    Journal: J Clin Neurosci; 2011 Nov; 18(11):1554-5. PubMed ID: 21868233.
    Abstract:
    We report a now 74-year-old patient who was successfully treated with a methotrexate (MTX)-ssbased polychemotherapy protocol (Bonn protocol) for primary central nervous system lymphoma (PCNSL) in 1996. When presenting with an unusually late relapse after 13 years of tumor-free survival the diagnosis was made on the basis of clinical and radiological criteria. In the context of the very limited treatment options for recurrent PCNSL, it is reassuring that the re-application of high dose-MTX-based polychemotherapy, including intraventricular treatment, again succeeded in a sustained complete response with still low neurotoxicity.
    [Abstract] [Full Text] [Related] [New Search]