These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: 5-deoxyflavones with cytotoxic activity from Mimosa diplotricha.
    Author: Lin LC, Chiou CT, Cheng JJ.
    Journal: J Nat Prod; 2011 Sep 23; 74(9):2001-4. PubMed ID: 21875046.
    Abstract:
    Bioassay-guided isolation of Mimosa diplotricha led to the isolation of four new 5-deoxyflavones, diplotrins A-C (1-3) and diplotasin (4), together with 12 known flavonoids, flavonolignans, and triterpenoids. On the basis of spectroscopic evidence, compounds 1-4 were characterized as 2',5'-dihydroxy-3,7,8,4'-tetramethoxyflavone (1), 3'-hydroxy-3,7,8,4'-tetramethoxyflavone (2), 2'-hydroxy-7,4',5'-trimethoxyflavone (3), and 4-hydroxy-3,10,11-trimethoxyisochromeno-[4,3-b]-chromen-7(5H)-one (4). The cytotoxic effects of these isolated compounds were evaluated against the A549, AGS, HT-29, and PC3 human cancer cell lines. Compounds 2 and 5″-methoxyhydnocarpin-D (5) showed the most potent antiproliferative activity.
    [Abstract] [Full Text] [Related] [New Search]