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  • Title: Hepatocellular carcinoma complicated by gastroduodenal obstruction: palliative treatment with metallic stent placement.
    Author: Lee YJ, Kim JH, Song HY, Park JH, Na HK, Kim PH, Fan Y.
    Journal: Cardiovasc Intervent Radiol; 2012 Oct; 35(5):1129-35. PubMed ID: 21882080.
    Abstract:
    PURPOSE: To evaluate the clinical effectiveness of self-expandable metallic stents in seven patients with malignant gastroduodenal obstruction caused by inoperable hepatocellular carcinoma (HCC). METHODS: Seven patients with gastroduodenal obstruction caused by advanced HCC underwent metallic stent placement from 2003 to 2010. These patients had total dysphagia (n = 5) or were able to eat only liquids (n = 2) before stent placement. Patients had Eastern Cooperative Oncology Group performance scores of 2 or 3, and Child-Pugh classification B or C. RESULTS: Stent placement was technically successful in all seven patients (100%) and clinically successful in six (86%). Five patients could eat a soft diet, and one patient tolerated regular diet after stent placement. Stent-related obstructive jaundice occurred in one patient. One patient had hematemesis 11 days after stent placement. Overall mean survival was 51 days (range, 10-119 days). Stent patency was preserved in six patients with clinical success until death. CONCLUSION: Placement of a covered self-expandable metallic stent may offer good palliation in patients with gastroduodenal obstruction due to advanced HCC.
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