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  • Title: Synthesis and antibacterial activity of aromatic and heteroaromatic amino alcohols.
    Author: de Almeida CG, Reis SG, de Almeida AM, Diniz CG, da Silva VL, Le Hyaric M.
    Journal: Chem Biol Drug Des; 2011 Nov; 78(5):876-80. PubMed ID: 21883957.
    Abstract:
    Two series of aromatic and heteroaromatic amino alcohols were synthesized from alcohols and aldehydes and evaluated for their antibacterial activities. All the octylated compounds displayed a better activity against the four bacteria tested when evaluated by the agar diffusion method and were selected for the evaluation of minimal inhibitory concentration. The best results were obtained for p-octyloxybenzyl derivatives against Staphylococcus epidermidis (minimal inhibitory concentrations = 32 μm).
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