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  • Title: Recurrent allograft antiglomerular basement membrane glomerulonephritis in a patient with Alport's syndrome.
    Author: Rassoul Z, al-Khader AA, al-Sulaiman M, Dhar JM, Coode P.
    Journal: Am J Nephrol; 1990; 10(1):73-6. PubMed ID: 2188508.
    Abstract:
    A patient with Alport's syndrome and chronic renal failure received a cadaver kidney graft. Four months after the transplantation, he developed glomerulonephritis induced by anti-glomerular basement membrane (GBM) antibody. The graft failed, and the patient returned to haemodialysis. Twenty-two months later the patient received a second cadaver kidney graft. Ten months after the second transplant, he developed a recurrent anti-GBM glomerulonephritis. This observation suggests that anti-GBM disease can recur in a second transplanted kidney in a patient with Alport's syndrome.
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