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  • Title: Synthesis of oligoribonucleotides containing 2'-O-methoxymethyl group by the phosphotriester method.
    Author: Efimov VA, Aralov AV, Chakhmakhcheva OG.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2011; 30(7-8):565-76. PubMed ID: 21888547.
    Abstract:
    An effective procedure for the synthesis of ribonucleotide monomers containing a 2 '-О-methoxymethyl-modifying group was developed. These monomers were used for the synthesis of RNA fragments by the solid-phase phosphotriester method under O-nucleophilic intramolecular catalysis. The properties of 2 '-О-methoxymethyl-containing oligoribonucleotides were examined.
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