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  • Title: Effect of tianeptine on cognitive functions in patients with depressive disorders during a 3-month observation.
    Author: Klasik A, Krysta K, Krupka-Matuszczyk I.
    Journal: Psychiatr Danub; 2011 Sep; 23 Suppl 1():S18-22. PubMed ID: 21894095.
    Abstract:
    OBJECTIVE: The authors put forward the hypotheses that during a three-month treatment with tianeptine in patients with depressive disorders there is an improvement in the short-term memory, reaction time and attention. SUBJECT AND METHODS: 20 patients suffering from depression, were included in the study. During the entire research period all patients were treated with monotherapy with tianeptine. Cognitive function measurements were performed using the Vienna Test System. RESULTS: Our study showed an improvement in the all the assessed functions: patients treated with tianeptine had better performance in tests measuring short term memory and learning processes as well as reaction time and attention. CONCLUSION: In conclusion, the study shows that tianeptine improves cognitive functions in depressed patients.
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