These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Relapse and recurrence in unipolar major depression: short-term and long-term approaches.
    Author: Thase ME.
    Journal: J Clin Psychiatry; 1990 Jun; 51 Suppl():51-7; discussion 58-9. PubMed ID: 2189875.
    Abstract:
    Relapse and recurrence following successful short-term treatment of major depression are common and vexing clinical problems. The risk of relapse and recurrence is reviewed, as is evidence pertaining to pharmacologic and psychosocial strategies for continuation and maintenance therapy. Up to 6 months' continuation treatment following short-term treatment response is recommended routinely for virtually all patients. Based on available evidence, a more prolonged course of maintenance pharmacotherapy is strongly recommended for patients with residual symptomatology and/or a past history of chronicity or multiple depressive episodes. Further research is necessary to identify the specific indications for combining psychotherapy and pharmacotherapy.
    [Abstract] [Full Text] [Related] [New Search]