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  • Title: [Uncomplicated malaria attack in an area with high chloroquine resistance. 2. Evaluation of first-choice therapeutic scheme].
    Author: Hengy C, Eberlé F, Arrive A, Kouka-Bemba D, Gazin P, Jambou R.
    Journal: Bull Soc Pathol Exot; 1990; 83(1):53-60. PubMed ID: 2190705.
    Abstract:
    The authors evaluate the comparative efficiency of chloroquine and amodiaquine (35 mg/kg during 3 days) for uncomplicated malaria treatment in an area with high chemoresistance level. 236 patients with malaria were examined and treated. 38% of them previously used antimalarials. The increase dosage in comparison with the WHO recommendations (25 mg/kg), lead to no advantages for chloroquine treatment (50% failure), in contrast with amodiaquine (4% failure). Therefore amodiaquine might be preferred in the health field unit for uncomplicated malaria.
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