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  • Title: Synthesis and biological evaluation of some novel triazol-3-ones as antimicrobial agents.
    Author: Pardeshi S, Bobade VD.
    Journal: Bioorg Med Chem Lett; 2011 Nov 01; 21(21):6559-62. PubMed ID: 21920741.
    Abstract:
    A new series of triazol-3-one derivatives bearing 4-methyl-4H-thieno[3',2': 5,6]thiopyrano[4,3-d][1,3]thiazolyl or 4-(thiophene-3-yl) thiazolyl moiety at 4-position and alkyl substitution at 2-position are synthesized. All the synthesized compounds are characterized by elemental analysis, IR, (1)H NMR, (13)C NMR, and mass spectral data. The newly synthesized compounds are screened for antifungal and antibacterial activities.
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