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  • Title: Lymphocytic hypophysitis accompanied by aseptic meningitis mimics subacute meningoencephalitis.
    Author: Suzuki K, Izawa N, Nakamura T, Hashimoto K, Ouchi K, Sakuta H, Asakawa Y, Numao A, Hirata K.
    Journal: Intern Med; 2011; 50(18):2025-30. PubMed ID: 21921390.
    Abstract:
    A 66-year-old man was admitted to our hospital with muscle pain, fatigue and appetite loss that had lasted for a month. The patient was somnolent and had nuchal stiffness with a high fever. Cerebrospinal fluid (CSF) tests demonstrated lymphocytic pleocytosis with a decreased CSF-blood glucose ratio. The tests for tuberculous, fungal and carcinomatous meningitis and herpetic meningoencephalitis were negative. Endocrinological exams showed hypopituitarism and diabetes insipidus. A pituitary MRI showed an enlargement of the pituitary stalk. A diagnosis of lymphocytic hypophysitis with aseptic meningitis was made after the exclusion of secondary hypophysitis. Lymphocytic hypophysitis with aseptic meningitis can mimic subacute meningoencephalitis.
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