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  • Title: [Characteristics of the postoperative period in diabetes mellitus type 1 in patients with distal splenorenal anastomosis].
    Author: Ivanov PA, Golikov PP, Shcherbiuk AN, Gvakhariia GN, Syromiatnikova ED, Guliaev VA, Nikolaeva NIu.
    Journal: Sov Med; 1990; (2):17-9. PubMed ID: 2192474.
    Abstract:
    Eight patients with type I diabetes mellitus have been operated on to form a distal splenorenal anastomosis (DSRA). A critical period (the 6th and the 7th days) postoperation has been observed when severe metabolic acidosis develops; to prevent its development, transfusions of 4% sodium bicarbonate solution (1.5-2.01) have been administered before the critical period for 24 hrs, with the metabolic condition monitored by biochemical analyses. Studies of metabolism in these patients after surgery have revealed a complete normalization of the acid-base balance and of potassium level, as well as a reduction of the blood glucose concentration. The doses of exogenic insulin have been reduced by 30%, this being associated with a tendency to an increase of the levels of endogenic insulin, C-peptide and glucagon of the blood. This helps a better stabilization of the diabetic process after the formation of a DSRA.
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