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  • Title: Dysgerminoma in a case of 46, XY pure gonadal dysgenesis (Swyer syndrome): a case report.
    Author: Han Y, Wang Y, Li Q, Dai S, He A, Wang E.
    Journal: Diagn Pathol; 2011 Sep 19; 6():84. PubMed ID: 21929773.
    Abstract:
    Simple 46, XY gonadal dysgenesis syndrome, also called Swyer syndrome, is known as pure gonadal dysgenesis. Individuals with the syndrome are characterized by 46, XY karyotype and phenotypically female with female genital appearance, normal Müllerian structures and absent testicular tissue. The condition usually first becomes apparent in adolescence with delayed puberty and primary amenorrhea due to the gonads have no hormonal or reproductive potential. Herein, we report a case of dysgerminoma diagnosed in a dysgenetic gonad of a 21-year-old patient with Swyer syndrome.
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