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  • Title: Carotid artery stenosis: performance of advanced vessel analysis software in evaluating CTA.
    Author: Tsiflikas I, Biermann C, Thomas C, Ketelsen D, Claussen CD, Heuschmid M.
    Journal: Eur J Radiol; 2012 Sep; 81(9):2255-9. PubMed ID: 21930358.
    Abstract:
    OBJECTIVES: The aim of this study was to evaluate time efficiency and diagnostic reproducibility of an advanced vessel analysis software for diagnosis of carotid artery stenosis. MATERIAL AND METHODS: 40 patients with suspected carotid artery stenosis received head and neck DE-CTA as part of their pre-interventional workup. Acquired data were evaluated by 2 independent radiologists. Stenosis grading was performed by MPR eyeballing with freely adjustable MPRs and with a preliminary prototype of the meanwhile available client-server and advanced visualization software syngo.via CT Vascular (Siemens Healthcare, Erlangen, Germany). Stenoses were graded according to the following 5 categories: I: 0%, II: 1-50%, III: 51-69%, IV: 70-99% and V: total occlusion. Furthermore, time to diagnosis for each carotid artery was recorded. RESULTS: Both readers achieved very good specificity values and good respectively very good sensitivity values without significant differences between both reading methods. Furthermore, there was a very good correlation between both readers for both reading methods without significant differences (kappa value: standard image interpretation k=0.809; advanced vessel analysis software k=0.863). Using advanced vessel analysis software resulted in a significant time saving (p<0.0001) for both readers. Time to diagnosis could be decreased by approximately 55%. CONCLUSIONS: Advanced vessel analysis application CT Vascular of the new imaging software syngo.via (Siemens Healthcare, Forchheim, Germany) provides a high rate of reproducibility in assessment of carotid artery stenosis. Furthermore a significant time saving in comparison to standard image interpretation is achievable.
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