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Title: The origin of biological homochirality. Author: Blackmond DG. Journal: Philos Trans R Soc Lond B Biol Sci; 2011 Oct 27; 366(1580):2878-84. PubMed ID: 21930578. Abstract: The single handedness of biological molecules has fascinated scientists and laymen alike since Pasteur's first painstaking separation of the enantiomorphic crystals of a tartrate salt over 150 years ago. More recently, a number of theoretical and experimental investigations have helped to delineate models for how one enantiomer might have come to dominate over the other from what presumably was a racemic prebiotic world. Mechanisms for enantioenrichment that include either chemical or physical processes, or a combination of both, are discussed in the context of experimental studies in autocatalysis and in the phase behaviour of chiral molecules.[Abstract] [Full Text] [Related] [New Search]