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  • Title: [Ultrasonic evaluation of spontaneous and drug-induced cycles in a sterile population].
    Author: Patriarca A, Giacardi M, Mossetti M, Pagliano M.
    Journal: Minerva Ginecol; 1990 Apr; 42(4):103-7. PubMed ID: 2193248.
    Abstract:
    The scope of this study was to correlate the size and number of growing follicles contemporeaneously in 106 spontaneous cycles and in 126 cycles induced by the administration of clomiphene, gonadotropins and LH-RH microinfusers, in a total of 149 sterile patients with a mean age of 30.2 years. The results have shown that maximum follicular diameter is significantly larger in drug-induced cycles in comparison to spontaneous cycles (p less than 0.05). Nonetheless, ultrasound examination alone is not sufficient to establish follicular development and the time for administering HCG in order to diminish the percentage of hyperstimulation syndromes. Additional biochemical and biological (E2) tests should therefore be performed, as well as a careful study of the endometrial response to induction therapy.
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