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Title: Molecular determinants that convert hormone sensitive lipase into gibberellin receptor. Author: Hirano K, Aya K, Matsuoka M, Ueguchi-Tanaka M. Journal: Protein Pept Lett; 2012 Feb; 19(2):180-5. PubMed ID: 21933120. Abstract: Gibberellins (GAs) are tetracyclic, diterpenoid plant hormones, essential for many developmental processes in higher plants. Plants perceive GA through a nuclear-localized GA receptor, GA INSENSITIVE DWARF1 (GID1). From sequence similarity, it is suggested that GID1 evolved from a hormone-sensitive lipase (HSL), and recent x-ray crystallography of the GA-GID1 complex has given insights into how GID1 recognizes GA. Analyses of the GA signaling pathway in several plant species further suggest that the GID1-mediated GA signaling pathway emerged in the vascular plant lineage and since then regulation of GA recognition specificity seems to have been fine tuned to strictly regulate the on-off GA signal.[Abstract] [Full Text] [Related] [New Search]