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  • Title: [The detection of nifedipine in biological materials].
    Author: Shormanov VK, Kvachakhiia LL, Markelov MIu, Konareva EG.
    Journal: Sud Med Ekspert; 2011; 54(4):31-4. PubMed ID: 21938941.
    Abstract:
    The objective of the present study was to find optimal conditions for the isolation of nifedipine from biological materials by ethylacetate. It was shown that nifedipine can be purified from co-extracted substances of the biological material on a Silasorb C-18 column with the size of the particles 30 microns. The authors propose to use thin-layer chromatography, IR spectrophotometry, and reverse-phase high performance liquid chromatography for the identification and quantitative determination of nifedipine extracted from cadaveric liver samples.
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