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  • Title: Patellofemoral and tibiofemoral articular cartilage and subchondral bone health following arthroscopic partial medial meniscectomy.
    Author: Wang Y, Dempsey AR, Lloyd DG, Mills PM, Wrigley T, Bennell KL, Metcalf B, Hanna F, Cicuttini FM.
    Journal: Knee Surg Sports Traumatol Arthrosc; 2012 May; 20(5):970-8. PubMed ID: 21946943.
    Abstract:
    PURPOSE: To examine articular cartilage and subchondral bone changes in tibiofemoral and patellofemoral joints following partial medial meniscectomy. METHODS: For this cross-sectional study, 158 patients aged 30-55 years, without evidence of knee osteoarthritis at arthroscopic partial medial meniscectomy (APMM), and 38 controls were recruited. MRI was performed once on the operated knee for each subcohort of 3 months, 2 or 4 years post-surgery, and the randomly assigned knee of the controls. Cartilage volume, cartilage defects, and bone size were assessed using validated methods. RESULTS: Compared with controls, APMM patients had more prevalent cartilage defects in medial tibiofemoral (OR = 3.17, 95%CI 1.24-8.11) and patellofemoral (OR = 13.76, 95%CI 1.52-124.80) compartments, and increased medial tibial plateau bone area (B = 143.8, 95%CI 57.4-230.2). Time from APMM was positively associated with cartilage defect prevalence in medial tibiofemoral (OR = 1.02, 95%CI 1.00-1.03) and patellofemoral (OR = 1.04, 95%CI 1.01-1.07) compartments, and medial tibial plateau area (B = 2.5, 95%CI 0.8-4.3), but negatively associated with lateral tibial cartilage volume (B = -4.9, 95%CI -8.4 to -1.5). The association of APMM and time from APMM with patellar cartilage defects was independent of tibial cartilage volume. CONCLUSIONS: Partial medial meniscectomy is associated with adverse effects on articular cartilage and subchondral bone, which are associated with subsequent osteoarthritis, in both tibiofemoral and patellofemoral compartments. LEVEL OF EVIDENCE: III.
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