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  • Title: An enhanced DNA fingerprinting service to investigate potential Clostridium difficile infection case clusters sharing the same PCR ribotype.
    Author: Fawley WN, Wilcox MH, Clostridium difficile Ribotyping Network for England and Northern Ireland.
    Journal: J Clin Microbiol; 2011 Dec; 49(12):4333-7. PubMed ID: 21956986.
    Abstract:
    Of 53 potential Clostridium difficile infection (CDI) case clusters/outbreaks, affecting 2 to 41 patients in 27 institutions, 19% comprised unrelated isolates and 34% had highly related and distinct isolates as shown by multilocus variable-number tandem-repeat analysis, despite sharing a common ribotype. These findings emphasize the value of enhanced fingerprinting to confirm or refute suspected CDI case clusters.
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