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  • Title: Protein degradation: BAGging up the trash.
    Author: Ast T, Schuldiner M.
    Journal: Curr Biol; 2011 Sep 27; 21(18):R692-5. PubMed ID: 21959156.
    Abstract:
    Cells efficiently uncover and degrade proteins that are misfolded. However, we know very little about what cells do to protect themselves from mislocalized proteins. A new study reveals a novel quality control pathway that recognizes and degrades secretory pathway proteins that have failed to target to the endoplasmic reticulum.
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