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  • Title: Effects of cytokinins, cytokinin ribosides and their analogs on the viability of normal and neoplastic human cells.
    Author: Casati S, Ottria R, Baldoli E, Lopez E, Maier JA, Ciuffreda P.
    Journal: Anticancer Res; 2011 Oct; 31(10):3401-6. PubMed ID: 21965753.
    Abstract:
    We examined the effects of some cytokinins and cytokinin ribosides including a series of adenosine analogs differently substituted in the N(6) position, along with some hypoxanthine derivatives on the viability of normal and neoplastic human cells. Cytokinins such as trans-zeatin, isopentenyladenine and benzyladenine do not show any effect, while cytokinin ribosides such as trans-zeatin riboside, isopentenyladenosine, and benzylaminopurine riboside impair the viability of normal and neoplastic cells, apart from colon carcinoma LoVo cells.
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