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  • Title: [The proteinase activity in the cell nuclei of rats following exposure to gamma radiation and methylnitrosourea].
    Author: Malakhova LV, Surkenova GN, Gaziev AI.
    Journal: Radiobiologiia; 1990; 30(3):312-6. PubMed ID: 2196633.
    Abstract:
    Activity of nuclear proteinases in blood and liver cells of rats exposed to whole-body gamma-irradiation (10 Gy) has been comparatively studied by the capacity of splitting the casein substrate. Proteinase activity in nuclei of irradiated rat leukocytes was shown to increase by 2.5 times and to gradually decrease after 48 h reaching 150-160% as compared to the control. Two hours following a single injection of methyl nitrosourea the alteration in the activity of proteinases in nuclei of rat hepatocytes and leukocytes was different from the alteration of this index after gamma-irradiation.
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