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  • Title: Comparison of an enzyme-immunoassay with a radio-immunoassay method for the detection of the hepatitis markers anti-HBs, anti-HBc and HBsAg.
    Author: Blackburn NK, Schoub BD, O'Connell KF.
    Journal: S Afr Med J; 1990 Jul 21; 78(2):102-3. PubMed ID: 2196700.
    Abstract:
    A comparative study was carried out on a radio-immunoassay (RIA) and enzyme-immunoassay (EIA) method for detecting the hepatitis markers anti-HBs, anti-HBc and HBsAg. The results indicated that the RIA and EIA were comparable for the HBsAg marker but that the RIA test was more sensitive for anti-HBs and more specific for anti-HBc. The conclusion was that if the EIA test is used for these markers, the laboratory and clinician must be aware of these limitations.
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