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  • Title: Implications of portal vein thrombosis after splenectomy for patients with idiopathic portal hypertension.
    Author: Hirashita T, Ohta M, Kai S, Masuda T, Eguchi H, Iwashita Y, Ogawa T, Kitano S.
    Journal: Surg Today; 2011 Nov; 41(11):1475-80. PubMed ID: 21969148.
    Abstract:
    PURPOSE: Idiopathic portal hypertension (IPH) is considered to be closely related to portal vein thrombosis (PVT). The aim of this study was to clarify the incidence, clinical characteristics, and outcomes of PVT in patients with IPH after splenectomy. METHODS: We investigated the rates, clinical characteristics, and outcomes of PVT in 18 patients who underwent splenectomy for IPH, during a mean follow-up period of 152 ± 83 months. RESULTS: Seven of the 18 patients (39%) experienced gastrointestinal bleeding, which was from the varices in 4. Eight patients (44%) had PVT, and the mean interval until its detection after splenectomy was 22 ± 41 months. The cumulative gastrointestinal bleeding rates 5, 10, and 15 years after surgery were 24%, 31%, and 41%, respectively. The cumulative survival rates 5, 10, and 15 years after surgery were 94%, 74%, and 65%, respectively. There were no significant differences in the cumulative gastrointestinal bleeding and survival rates between patients with and those without PVT. CONCLUSION: Despite the high incidence of PVT in IPH patients postsplenectomy, it may not be related to their gastrointestinal bleeding or prognosis.
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