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  • Title: A chemical investigation of the Antarctic sponge Lyssodendoryx flabellata.
    Author: Cutignano A, De Palma R, Fontana A.
    Journal: Nat Prod Res; 2012; 26(13):1240-8. PubMed ID: 21978171.
    Abstract:
    From the Antarctic sponge Lyssodendoryx flabellata, a new polycyclic compound, which we named flabellone, related to the oestrogenic hormone oestrone, has been elucidated by spectrometric and spectroscopic means. Along with flabellone, a glycosphingolipid (GSL) mixture featuring an unusual α-fucofuranosyl-3-β-glucopyranoside unit structurally identical to the previously reported terpioside has been isolated and identified. The mixture of GSL homologues exhibited inhibitory effects in mixed lymphocyte reactions on human cells.
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