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  • Title: Pyrazinamide-induced anaphylaxis: diagnosed by skin test and successful desensitization.
    Author: Bavbek S, Yılmaz I, Aydın Ö, Ozdemir SK.
    Journal: Int Arch Allergy Immunol; 2012; 157(2):209-12. PubMed ID: 21986254.
    Abstract:
    Pyrazinamide (PZA), an antituberculosis drug, may cause hypersensitivity reactions. Here, we report a case of anaphylaxis secondary to a PZA administration for tuberculosis pleuritis. To the best of our knowledge, this is the first reported case of strongly possible IgE-mediated, PZA-induced anaphylaxis proved by skin prick test and oral provocation/desensitization.
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